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Oxycodone, sold under the brand name OxyContin among others, is an opioid medication used for treatment of moderate to severe pain, and a common drug of abuse. It is usually taken by mouth, and is available in immediate-release and controlled-release formulations.

The main ingredient in Oxycontin is a long-acting formulation of oxycodone. However, the names Oxycontin and oxycodone are often used interchangeably. Oxycodone, also referred to as the “oxy drug,” is a morphine-like chemical derived from part of the opium plant. Oxycodone works by interacting with the central nervous system to trigger relaxation and pain relief.

The difference between Oxycontin and oxycodone is that Oxycontin only refers to the extended-release formulation. Oxycontin is meant to treat chronic pain. Oxycodone, the active ingredient in Oxycontin, is available by itself as an immediate-release (IR) formulation or in combination with other pain medications. Immediate-release formulations, such as Oxycontin IR, are for treating pain on an as-needed basis. Oxycodone 30 mg is the highest dose of IR oxycodone available. There is also an Oxycontin 30 mg dose, and the brand’s highest dose is Oxycontin 80 mg.

What Is Oxycontin Used For?

Oxycontin is used for severe, chronic pain. It is prescribed to patients with major injuries, cancer, arthritis and other conditions that require long-acting relief from pain. Oxycontin is also used for people with opioid tolerance. Opioid tolerance happens when a patient has been taking opioid medications for a long time. After a while, their bodies no longer respond to the opioid and higher doses are needed to relieve their pain. Oxycontin doses above 40 mg per tablet are reserved for these opioid-tolerant patients.

Since it provides up to 12 hours of relief, Oxycontin is only for chronic conditions. Immediate-release oxycodone must be taken every four to six hours to manage around-the-clock pain. For the same nonstop pain, a patient only needs to take Oxycontin twice a day.

If not taken correctly, a patient can become addicted to Oxycontin. The misuse or nonmedical use of Oxycontin can cause overdose and death. Chewing, crushing, snorting or injecting Oxycontin bypasses the extended-release mechanism. This causes a large, uncontrolled amount of oxycodone to be released into the body. The flood of oxycodone gets the individual high, but it also causes severe depression of bodily functions such as breathing.

Dosage and Administration

A safe maximum dose of Oxycontin a person should take per day has not been defined. However, there are some guidelines to follow. In general, it is recommended that Oxycontin doses start low and then be increased until the dose is high enough for pain relief but still low enough to avoid side effects. Patients who lack opioid tolerance should not take more than 80 mg of Oxycontin in one day.

Opioid-tolerant patients can be prescribed higher doses to achieve pain relief as long as they do not experience negative side effects. This amount is unique to the patient and should be closely monitored by a doctor. The risk of overdose and death is twice as high for patients taking more than 60 mg of Oxycontin in a day. However, there are case reports of individuals functioning well at close to 1000mg of Oxycontin in a day.

Regardless of the dose, it is important to take Oxycontin exactly as prescribed. Oxycontin pills (Oxy pills) are designed to release a steady amount of oxycodone into a person’s system over the course of 12 hours. For this reason, the pills must be swallowed one at a time, whole, with enough water to ensure that the pill makes it all the way down the throat. Taking Oxycontin any other way can lead to overdose and death.

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